Ebook Farmakologi : Pharmacology For Nurses Second Edition
Pharmacology For Nurses Second Edition
In modern health care, there is an increasing
reliance on medication therapy to manage
illness and disease, to slow progression of dis-
ease, and to improve patient outcomes. Medi-
cations offer a variety of potential benefits
to the patient: relief of symptoms, support
for necessary physiological processes, and
destruction of toxic substances or organisms
that cause disease, to name a few. Yet medica-
tions also have the potential to do harm, even
when administered properly—and the harm
is likely to be exacerbated if medications are
administered incorrectly. The administration
of drugs introduces opportunity to affect
either remedy or harm.
As the persons most often charged with
administering medications to patients, nurses
can minimize any harm associated with med-
ications by carrying out this task with few,
if any, errors (Institute of Medicine [IOM],
2007). A 2007 IOM (now the National Acad-
emy of Science) report on medication safety,
titled Preventing Medication Errors, empha-
sized the urgency of reducing medication er-
rors, improving communication with patients,
continually monitoring for medication errors,
providing clinicians with decision-support
and information tools, and improving and
standardizing medication labeling and
drug-related information (IOM, 2007).
If one of nursing’s primary roles is the safe
administration of medications, it is important
to realize that this requires knowing not only
how to correctly administer medications to
patients, but also how to determine whether
the intended effects are achieved and whether
any adverse, or unintended, effects have oc-
curred. Without adequate understanding of
drugs and their effects on the body, nurses are
unable to meet their professional and legal re-
sponsibilities to their patients. This text will
provide the reader with that knowledge.
Nursing and Pharmacology
Pharmacology is the study of the ac-
tions of drugs, incorporating knowledge
from other interrelated sciences, such as
pharmacokinetics (how the body absorbs, dis-
tributes, metabolizes, and excretes a drug) and
pharmacodynamics (a drug’s mechanism of
action and effect on an organism). Knowledge
of the various drug classes enables the nurse
to understand how drugs work in the body,
to achieve the therapeutic (intended) effects,
and to anticipate and recognize the potential
side effects (unintended or unavoidable) or
toxicities. To understand the pharmacology of
drugs, and related information, such as drug
interactions and side effects, it is important to
understand drugs’ mechanisms of action, at
the molecular level. Rather than merely un-
derstanding a drug’s actions, interactions, side
effects and dosage requirements, the nurse
should strive to understand the process be-
hind these elements of drug administration.
This requires at least a fundamental under-
standing of drug–drug receptor interactions,
even if at an elementary “lock and key” level.
Only then will drug effects, interactions, and
side effects, and the logic behind dosing regi-
mens, reveal a complete picture. Chapter 2
continues this discussion in depth.
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